CRYSVITA® (burosumab-twza)
targets
the underlying
cause of XLH

CRYSVITA is an antibody that treats the underlying cause of X-linked hypophosphatemia (XLH) by increasing phosphorus levels in the body. People with XLH have too much of a protein called fibroblast growth factor 23 (FGF23), which causes the body to lose much of the phosphorus it needs for bone health.

How CRYSVITA may work
Tim, age 28,
living with XLH

CRYSVITA for children

The benefits and risks of CRYSVITA treatment were studied in a total of 126 children with XLH.

Image of child for benefits and risk of CRYSVITA® treatment
Image of child for benefits and risk of CRYSVITA® treatment

In these clinical studies, CRYSVITA was
shown to help by:

Increased phosphorus levels in children icon

Increasing and maintaining phosphorus levels in the blood

Healing of rickets in children icon

Healing rickets and helping improve leg abnormalities

Increased growth in children icon

Increasing growth

See results for children

CRYSVITA for adults

The benefits and risks of CRYSVITA treatment were studied in a total of 148 adults with XLH.

Image of adult for benefits and risks of CRYSVITA® treatment
Image of adult for benefits and risks of CRYSVITA® treatment

In these clinical studies, CRYSVITA was
shown to help by:

Increased phosphorus levels in adults icon

Increasing and maintaining phosphorus levels in the blood

Healing of fractures and osteomalacia in adults icon

Healing fractures and osteomalacia

Improved XLH-related joint stiffness in adults icon

Improving XLH-related joint stiffnesss

See results for adults