Learn how CRYSVITA targets the underlying cause of
X-linked hypophosphatemia (XLH) by helping to restore the balance of phosphorus in the body.
Under normal conditions, a protein called fibroblast growth factor 23 (FGF23) helps maintain just the right amount of phosphorus in the body. When FGF23 works well, the extra phosphorus the body doesn’t need is eliminated in the urine, and a normal amount of phosphorus is retained in the blood.
Adults and children with XLH don’t have enough phosphorus because the activity of FGF23 in their bodies is abnormal. Without enough phosphorus, bones cannot grow or heal properly, leading to the symptoms of XLH.
CRYSVITA is an antibody that helps to keep a normal amount of phosphorus in the body by keeping FGF23 activity in check.
