TIO resources for you and your family

CRYSVITA Patient Brochure

Take a proactive approach and make the most of your visit with your doctor.

Download the CRYSVITA Patient Brochure >

CRYSVITA Patient Brochure

Take a proactive approach and make the most of your visit with your doctor.

CRYSVITA® resources & patient brochure

Connect with a community of support for tumor-induced
osteomalacia (TIO)

NIH Genetic and Rare Diseases Information Center (GARD)

GARD maintains a list of rare diseases and related terms to help people find reliable information about their disease.

GARD is resource that maintains a list of rare diseases and related terms to help people find information about their disease
National Organization for Rare Disorders (NORD)

NORD is a patient advocacy organization dedicated to individuals with rare diseases and the organizations that serve them.

NORD is a patient advocacy organization committed to helping patients with rare diseases
XLH Network

The XLH Network is a global patient support organization for people with X-linked hypophosphatemia (XLH) and caregivers. The website contains educational materials about XLH and other disorders that cause hypophosphatemia for patients and medical professionals.

XLHNetwork.org is an organization that supports people with XLH

Glossary

antibody

A protein that is made by the immune system or a protein that is modified in a lab to recognize and block a target that threatens the body’s normal function.

fibroblast growth factor 23 (FGF23)

A protein that plays a role balancing the amount of phosphorus in the body. In TIO, the activity of FGF23 is abnormally increased, throwing off the balance of phosphorus.

hypophosphatemia

Low levels of phosphorus in the blood.

mineralization

A process where minerals like phosphorus are deposited in the bone, causing the bones to harden.

osteoid

A starting component for building bone where minerals have not yet been deposited; an unmineralized component of bone.

osteoid volume to bone volume (OV/BV)

A ratio of unmineralized bone to mineralized bone. In TIO, this ratio is large, pointing to a greater presence of unmineralized bone.

osteomalacia

A softening and weakening of the bones in children and adults caused by deficiencies in vitamin D, calcium, or phosphate.

phosphorus

A mineral that is important for proper bone development and repair.

serum phosphorus

Amount of phosphorus in the blood.

vitamin D

A nutrient used by the body to maintain strong bones.